Epitalon

A synthetic tetrapeptide based on the natural peptide epithalamin produced by the pineal gland. While primarily known as an anti-aging peptide through telomerase activation, Epitalon plays a significant role in sleep regulation by normalizing melatonin production from the pineal gland, which declines with age. This makes it particularly valuable for age-related sleep disturbances and circadian rhythm dysregulation.

• Stimulates pinealocytes to restore melatonin synthesis and secretion
• Reactivates genes involved in circadian clock regulation
• Activates telomerase enzyme (hTERT) for anti-aging effects
• Enhances antioxidant defense enzymes (SOD, catalase) to reduce oxidative sleep disruption

• Active cancer (telomerase activation could theoretically promote tumor growth)
• Autoimmune conditions without medical supervision
• Pregnancy or breastfeeding

Store at 2–8°C (36–46°F) for up to 3 months. For long-term storage, keep at -20°C (-4°F). Once reconstituted, refrigerate and use within 21 days.

Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. A key study in elderly patients (ages 60-80) demonstrated that Epitalon restored evening melatonin peaks to levels resembling those of younger adults, with corresponding improvements in sleep quality and daytime alertness. The 15-year longitudinal study showed improved immune function, cardiovascular health, and endocrine balance alongside the sleep benefits. Its dual role in melatonin restoration and telomere elongation makes it uniquely positioned among sleep-supportive peptides.