GHRP-2

A synthetic hexapeptide GH secretagogue considered the most potent in the GHRP family. It produces strong GH release through the ghrelin receptor with moderate effects on appetite, cortisol, and prolactin, falling between GHRP-6 and ipamorelin in selectivity.

• Potently agonizes the GHS-R1a receptor, producing the largest GH pulse among GHRPs
• Stimulates hypothalamic GHRH neurons to amplify GH release
• Moderate ghrelin-like signaling increases appetite through NPY/AgRP pathway activation

• Active cancer or tumors
• Pregnancy or breastfeeding
• Conditions aggravated by elevated cortisol
• Uncontrolled diabetes

Store at 2–8°C (36–46°F) for up to 3 months. For long-term storage, keep at -20°C (-4°F). Once reconstituted, refrigerate and use within 21 days. Protect from light.

GHRP-2 (Pralmorelin) has been approved in Japan as a diagnostic agent for GH deficiency and extensively studied in clinical settings. Research demonstrates it produces the highest peak GH levels among GHRPs, approximately 20-40% greater than GHRP-6. Studies also suggest neuroprotective effects in models of neurodegeneration.