NA-Selank

An acetylated analog of Selank with improved metabolic stability and enhanced blood-brain barrier penetration compared to the parent peptide. The N-acetyl modification protects against aminopeptidase degradation, extending its effective duration of action and potentially increasing central nervous system bioavailability.

• Same GABAergic and serotonergic modulation as Selank with improved pharmacokinetic profile
• N-acetyl group confers resistance to aminopeptidase degradation
• Enhanced blood-brain barrier penetration increases central anxiolytic and nootropic activity
• Retains tuftsin-derived immunomodulatory properties

• Pregnancy or breastfeeding
• Active autoimmune conditions
• Known hypersensitivity to Selank or tuftsin-derived peptides

Store at 2–8°C (36–46°F) for up to 3 months. For long-term storage, keep at -20°C (-4°F). Once reconstituted, refrigerate and use within 21 days. Protect from light.

NA-Selank is a pharmacokinetically optimized derivative of Selank designed to overcome the rapid enzymatic degradation that limits the parent peptide's duration of action. While standard Selank has extensive Russian clinical data, the acetylated form has been studied primarily in in vitro and preclinical settings. Research confirms the N-acetyl modification significantly extends the peptide's plasma half-life while preserving its anxiolytic and immunomodulatory pharmacology. It is widely used in research communities as an enhanced-stability alternative to Selank.