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Healing & RecoveryPreclinicalIntermediate

TB4-FRAG

Thymosin Beta-4 Fragment

Also known as: TB-500 Fragment, TB4 Fragment 17-23, Ac-LKKTETQ

Overview

An active fragment of Thymosin Beta-4 encompassing the actin-binding domain. Retains key healing properties of the full molecule in a smaller, more targeted form with potentially improved tissue-specific activity.

Half-Life
~1 hour
Typical Dose
250–750 mcg
Frequency
1x daily or every other day
Cycle Length
4-8 weeks

Administration

SubcutaneousIntramuscular

Benefits

  • Targeted tissue repair signaling
  • Promotes cell migration to injury sites
  • Anti-inflammatory properties
  • Smaller molecule size for better tissue penetration
  • Supports wound healing

Side Effects

  • Injection site irritation
  • Mild fatigue (rare)
  • Headache (uncommon)

Mechanism of Action

  • Binds G-actin to promote cell motility
  • Modulates actin polymerization at injury sites
  • Reduces NF-kB driven inflammatory signaling

Contraindications

  • Active malignancy
  • Pregnancy or breastfeeding
  • Known hypersensitivity to thymosin peptides

Storage & Reconstitution

Store at 2–8°C (36–46°F) for up to 3 months. For long-term storage, keep at -20°C (-4°F). Once reconstituted, refrigerate and use within 2 weeks.

Common peptide amounts:2 mg5 mg10 mg

Research Summary

Preclinical research indicates that the active fragment retains the core actin-binding and cell-migration-promoting properties of full-length Thymosin Beta-4. Limited human data; primarily studied in vitro and in animal models.

Commonly Stacked With

Healing & RecoveryBPC-157
Healing & RecoveryGHK-Cu

This information is for educational purposes only. Always consult a qualified healthcare professional before using any peptide.