Thymogen

A synthetic dipeptide (L-glutamyl-L-tryptophan) developed as the minimal active fragment responsible for thymic immunomodulation. Used clinically in Russia as a nasal spray for immune support and prevention of respiratory infections.

• Activates thymic epithelial cell signaling for thymocyte maturation
• Enhances phagocytic activity of neutrophils and macrophages
• Increases natural killer cell cytotoxicity
• Modulates production of thymic hormones and growth factors
• Restores suppressed immune parameters after radiation or chemotherapy

• Pregnancy or breastfeeding
• Organ transplant recipients
• Active autoimmune disease flare

Store at 2–8°C (36–46°F) for up to 3 months. Nasal spray: store at room temperature and use within 10 days of opening. Once reconstituted (injectable), refrigerate and use within 48 hours.

Developed at the St. Petersburg Institute of Bioregulation and Gerontology. Approved and marketed in Russia as an intranasal immune stimulant. Published Russian clinical studies show reduced incidence of respiratory infections and improved immune parameters in immunocompromised patients. Limited English-language peer-reviewed publications.