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Anti-AgingResearch OnlyBeginner

Vilon

Vilon (Lys-Glu Dipeptide)

Also known as: KE dipeptide, Lys-Glu, T-38

Overview

An ultra-short bioregulator peptide consisting of just two amino acids (lysine-glutamic acid) developed by the Khavinson research group. Despite its minimal size, Vilon demonstrates significant immunomodulatory and gene-regulatory effects, particularly on thymic function and T-cell immunity. It represents the smallest known peptide with documented bioregulatory activity.

Half-Life
~30-60 minutes
Typical Dose
0.5–1 mg
Frequency
Once daily for 10-15 day cycles
Cycle Length
10-15 days on, 3-6 months off

Administration

OralSubcutaneousIntranasal

Benefits

  • Supports thymic function and T-cell immunity
  • Modulates gene expression related to immune regulation
  • Oral bioavailability (rare for peptides)
  • Extremely well-tolerated with minimal side effects

Side Effects

  • Generally very well tolerated
  • Rare mild gastrointestinal discomfort (oral route)
  • Occasional injection site irritation

Mechanism of Action

  • Interacts with DNA regulatory sequences to modulate immune gene expression
  • Promotes thymic peptide production and T-cell differentiation
  • Regulates cytokine balance for immune homeostasis

Contraindications

  • Active autoimmune conditions (use with caution)
  • Immunosuppressive therapy
  • Pregnancy or breastfeeding

Storage & Reconstitution

Store capsules at room temperature (15–25°C (59–77°F)). Injectable form: store at 2–8°C (36–46°F). Highly stable due to small size.

Common peptide amounts:5 mg10 mg

Research Summary

Research by the St. Petersburg Institute of Bioregulation and Gerontology has shown that Vilon can modulate expression of genes involved in immune regulation, cell differentiation, and apoptosis. Studies in aged animals demonstrated restored thymic structure and function. The dipeptide's ability to exert biological effects despite its tiny size challenges conventional pharmacological assumptions and has implications for oral peptide drug development. Published data spans over two decades of Russian bioregulatory research.

Commonly Stacked With

Anti-AgingThymalin
Anti-AgingEpithalon
Anti-AgingPinealon

This information is for educational purposes only. Always consult a qualified healthcare professional before using any peptide.